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INS — RAPGEF4

Text-mined interactions from Literome

Kashima et al., J Biol Chem 2001 : In the present study, we investigated the role of the cAMP-GEFII -- Rim2 pathway in incretin potentiated insulin secretion in native pancreatic beta-cells ... The effect of cAMP-GEFII on insulin secretion is mediated by Rim2 and depends on intracellular calcium as well as on cAMP
Leech et al., Vitam Horm 2010 : Epac2 dependent rap1 activation and the control of islet insulin secretion by glucagon-like peptide-1
Ying et al., FEBS Lett 2012 (Synaptic Transmission) : Knock-down of syntabulin by shRNA reduced both basal and glucose stimulated insulin secretion, and diminished cAMP-Epac2 and cAMP-PKA potentiated insulin secretion