Gene interactions and pathways from curated databases and text-mining

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RELA — TOLLIP

Text-mined interactions from Literome

Bulut et al., J Immunol 2001 : Moreover, we show that Toll interacting protein (Tollip) coimmunoprecipitates with TLR2 and TLR4 using HEK 293 cells, and overexpression of Tollip inhibits NF-kappaB activation in response to TLR2 and TLR4 signaling
Li et al., Mol Immunol 2004 : We demonstrated that overexpression of Tollip inhibited NFkB reporter gene transcription
Cario et al., Mol Immunol 2005 : This brief review summarizes the current understanding of Toll-like receptor ( TLRs ) mediated intestinal epithelial mechanisms of commensal tolerance versus intolerance and provides an update on the downstream negative control of signaling responses through decreased surface expression, interregulation with NOD2, overexpression of Tollip , various inhibitors of NF-kappaB as well as soluble tolerizing mediators present in lumen and serum which all may maintain or -- when dysregulated -- impair mucosal homeostasis in health or disease, respectively
Hu et al., Frontiers in bioscience (Landmark edition) 2009 (Cardiomegaly) : Overexpression of Tollip also reduced NF-kappaB binding activity by 30.7 percent and phospho-p38 by 47.1 percent, respectively