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DYNLRB1 — NFKB1
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O'Sullivan et al., J Surg Res 2009
(Inflammation) :
The role of P38 MAPK and PKC in
BLP induced TNF-alpha release, apoptosis, and
NFkappaB activation in THP-1 monocyte cells ... In this study, we set out to examine the precise role of both protein kinase C ( PKC ) and P38 MAPK signaling kinases in
bacterial lipoprotein (BLP) induced
nuclear factor-kappa B (NFkappaB) activation and tumor necrosis factor-alpha (TNFalpha) release in THP-1 monocytic cell line ... PMA and
BLP induced rapid nuclear translocation of
NFkappaB , which was inhibited by pretreatment with both SB-202190 and bis I, and SB202190 but not bis I, respectively
Li et al., Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 2010
:
BLP stimulation
resulted in dose dependent
NF-KappaB activation in HEK293 cells stably expressing TLR2
Liu et al., J Immunol 2010
:
Furthermore, overexpression of ST2 dose-dependently attenuated
BLP induced
NF-kappaB activation, suggesting a negative regulatory role of ST2 in TLR2 signaling