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CEP63 — JAK2
Text-mined interactions from Literome
Plo et al., Blood 2008
(Myeloproliferative Disorders...) :
Moreover,
JAK2 activation
increased centrosome and ploidy abnormalities
Santos et al., Blood 2010
(Polycythemia Vera...) :
Phase 2 study of
CEP-701 , an orally available
JAK2 inhibitor , in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis
Stump et al., Arthritis Res Ther 2011
(Arthritis, Experimental...) :
In this paper, we describe the efficacy profile of
CEP-33779 , a highly selective, orally active, small-molecule
inhibitor of
JAK2 evaluated in two mouse models of RA