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BMP2 — PPARG

Text-mined interactions from Literome

Hata et al., Mol Biol Cell 2003 : In C3H10T1/2 cells, BMP2 induced expression of PPARgamma along with adipogenesis ... Specific inhibitors for p38 kinase inhibited BMP2 induced adipocytic differentiation and transcriptional activation of PPARgamma , whereas overexpression of Smad6 had no effect on transcriptional activity of PPARgamma
Hansmann et al., J Clin Invest 2008 (Hypertension, Pulmonary) : Both BMP-2 and a PPARgamma agonist stimulated production and secretion of apoE by SMCs. Using a variety of methods, including short hairpin RNAi in human PASMCs, PAH patient derived BMP-RII mutant PASMCs, a PPARgamma antagonist, and PASMCs isolated from PPARgamma- and apoE-deficient mice, we demonstrated that the antiproliferative effect of BMP-2 was BMP-RII, PPARgamma , and apoE dependent
Kato et al., Life Sci 2009 : BMP-2 increased not only mRNA and protein expressions of Dlx5 followed by inducing Osterix and BSP levels in a dose- and time dependent manner with an increase in Runx2, Msx2, AJ18, ALP and OC levels, but also induced PPARgamma2 and aP2 levels