Gene interactions and pathways from curated databases and text-mining

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LPA — NEUROD4

Text-mined interactions from Literome

Rhee et al., Neuroreport 2006 : To study the roles of LPA in neuronal differentiation , we determined whether LPA activates CREB in H19-7, hippocampal progenitor cells
Moughal et al., J Neurochem 2006 : These findings suggest a novel role for the constitutively active LPA ( 1 ) receptor in regulating NGF induced neuronal differentiation
Dottori et al., Stem Cells 2008 : LPA acts through the activation of the Rho/ROCK and the phosphatidylinositol 3-kinase/Akt pathways to inhibit neuronal differentiation
Goldshmit et al., Am J Pathol 2012 (Disease Models, Animal...) : This antibody, B3, specifically binds LPA, prevents it from interacting with its complement of receptors, and blocks LPA 's effects on the neuronal differentiation of human neural stem/progenitor cells, demonstrating its specificity toward LPA signaling
Frisca et al., J Lipid Res 2013 : We previously reported that lysophosphatidic acid (LPA) inhibits the neuronal differentiation of human embryonic stem cells ( hESC ) ... Furthermore, LPA inhibited the neuronal differentiation of iPSCs