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HMGA1 — IL2
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Kim et al., Immunity 2001
:
Moreover,
IL-2 induces the binding of
HMG-I(Y) , Stat5a, and Stat5b in vivo to PRRIV and PRRIII, which also functions as an IL-2 response element
Kim et al., EMBO J 2002
:
Whereas
IL-2 responsiveness
requires Stat5 and
HMG-I(Y) binding, TCR responsiveness of PRRIV requires two AP-1- and two NFAT binding sites that bind Jun, Fos and NFAT family members in vitro and in vivo
Fedele et al., Oncogene 2005
(Cell Transformation, Neoplastic...) :
The
HMGA1 induced expression of
IL-2 and IL-15 proteins and their receptors may account for the onset of these lymphomas
Lewis et al., Mol Cell Biol 1994
:
Mutational analysis of the -127/-118 NF-kappa B site indicates that both NF-kappa B and
HMG-I(Y) binding at this site are
essential for
interleukin-1 induction of the promoter