Gene interactions and pathways from curated databases and text-mining

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EIF4E — STX1A

Text-mined interactions from Literome

Colpoys et al., Cell Signal 2005 : Treatment with the p38 inhibitor, SB202190, or either of the ERK1/2 inhibitors, PD98059 and U0126, partially blocked Stx1 induced eIF4E phosphorylation
Cherla et al., J Leukoc Biol 2006 (MAP Kinase Signaling System) : Stx1 increased eukaryotic translation initiation factor 4E ( eIF4E ) activation by 4.3-fold within 4-6 h, and LPS or Stx1 + LPS treatment increased eIF4E activation by 7.8- and 11-fold, respectively, within 1 h. eIF4E activation required Stx1 enzymatic activity and was mediated by anisomycin, another ribotoxic stress inducer