Gene interactions and pathways from curated databases and text-mining

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IL2 — NPY4R

Text-mined interactions from Literome

Ruhul Amin et al., Oncogene 2002 : In addition, PP1 substantially inhibited the IL-2beta- and TNFalpha dependent activation of Erk 1/2 and Akt
Ross et al., J Biol Chem 2010 : Moreover, inhibition of PP2A, but not PP1 , diminished IL-2 induced tyrosine phosphorylation of IL-2Rbeta , JAK3, and STAT5, and abolished STAT5 DNA binding activity
Matsuzawa et al., Biochem Biophys Res Commun 1993 : IL-2 induces transient and specific decrease in cytosolic protein phosphatase PP1 activity in murine T cell lines ... In the IL-2 dependent murine cytotoxic T cell line CTLL-2, IL-2 induced a rapid and transient decrease in Co ( 2+ ) -trypsin treated activity of protein phosphatase PP1
Brockdorff et al., Cytokine 1997 : We show that calyculin A, a potent inhibitor of PP1 and PP2A, blocks PP1/PP2A activity and IL-2 induced adhesion, whereas cyclosporin A, an inhibitor of protein serine/threonine phosphatase 2B (PP2B), does not, suggesting that PP1 and/or PP2A are involved in IL-2 induced adhesion