◀ Back to INS
APOE — INS
Text-mined interactions from Literome
Vergès et al., Diabetes Metab 2001
(Diabetes Mellitus, Type 2...) :
Indeed,
insulin stimulates
apoB/E receptor ( LDL-receptor ) activity and enhances LDL degradation via the LDL-receptor pathway
Yue et al., J Biol Chem 2004
:
Neither
insulin nor a peroxisome proliferator activated receptor ( PPAR) alpha agonist
regulated adipocyte
apoE gene expression
Titiov et al., Vestn Ross Akad Med Nauk 2005
:
INS initiated the synthesis of
apoE and active receptor uptake of FA by cells in the form of triglycerides through apoE/B- 100 receptor endocytosis
Fishel et al., Arch Neurol 2005
(Hyperinsulinism...) :
Increased inflammation was modulated by
insulin induced changes in CSF levels of norepinephrine and
apolipoprotein E ( both P < .05 )
Lei et al., Biochem Biophys Res Commun 2008
:
We found that ApoE4 can strongly bind to amylin, and
insulin can hardly
inhibit amylin-ApoE binding
Du et al., Neurosci Lett 2009
:
We report here that, in comparison with ApoE2 and ApoE3,
ApoE4 significantly
reduces levels of
insulin degrading enzyme (IDE) , which is responsible for the cellular clearance of Abeta in neurons
Liu et al., J Neurosci Methods 2012
:
Insulin increases central
apolipoprotein E levels as revealed by an improved technique for collection of cerebrospinal fluid from rats