Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Weir et al., Am J Hypertens 1999 (Hypertension...) : Angiotensin II receptor blockers are currently being evaluated in comparison with other therapies in two large clinical trials of non-insulin dependent diabetic nephropathy with proteinuria to assess impact on the rate of progression of renal disease
Klein et al., Acad Med 2002 (Diabetes Mellitus, Type 2) : Other diabetes related topics include wound healing ( epithelium ), basement membrane thickening ( connective tissue ), insulin regulation of muscle metabolism, diabetic neuropathy ( neurohistology ), platelet adhesiveness, glycation and HbA1c ( blood ), osteoporosis and Charcot joints ( skeletal system ), autoimmune mechanisms ( cellular immunology ), atherosclerosis and high blood pressure ( blood vessels ), diabetic nephropathy ( renal ), altered hepatic and gastrointestinal function, impotence ( male reproductive system ), and a comparison of type I and type II diabetes ( endocrine system )
Li et al., Kidney Int 2003 (Diabetes Mellitus, Type 2...) : Up-regulation of OPN expression may play a role in tubulointerstitial injury associated with diabetic nephropathy, and blockade of the RAS by ramipril may confer renoprotection by decreasing OPN expression in non-insulin dependent diabetic nephropathy
Yasuda et al., Am J Hypertens 2004 (Diabetic Nephropathies...) : Thirty-four hypertensive patients with non-insulin dependent diabetic nephropathy underwent ABPM before and after treatment with perindopril ( final dose : 4.9 +/- 1.8 mg/d )
Björck et al., BMJ (Clinical research ed.) 1992 (Diabetic Nephropathies...) : 40 patients with insulin dependent diabetes and diabetic nephropathy with reduced renal function
Yamabe et al., J Pharm Pharmacol 2006 (Diabetes Mellitus, Type 2...) : A previous study showed that Hachimi-jio-gan has a protective effect in rats subjected to subtotal nephrectomy plus streptozotocin injection, a model of insulin dependent ( type 1 ) diabetic nephropathy
Gumustekin et al., Ren Fail 2013 : This study was designed to evaluate the renoprotective effect of insulin on diabetic nephropathy through Rac1 inhibition
Whiteside et al., Clin Invest Med 1987 (Albuminuria...) : To determine the specificity of the urine excretion of albumin as a measure of glomerular permeability in early insulin dependent diabetic nephropathy , the effect of variable glomerular filtration and urine flow rates on albumin, beta 2-microglobulin excretion, and the fractional renal clearance of neutral dextran ( Stokes Einstein Radius 24-46 A ) was examined
Mangili et al., N Engl J Med 1988 (Diabetes Mellitus, Type 1...) : We have studied the activity of sodium-lithium countertransport in red cells, a marker of risk for essential hypertension, in white European adults with insulin dependent diabetes and diabetic nephropathy , a matched group of patients with diabetes without renal disease, and nondiabetic patients with renal disease
Nordén et al., Acta Med Scand 1984 (Diabetes Mellitus, Type 1...) : Forty-seven patients with insulin dependent diabetes ( IDDM ) and diabetic nephropathy and 47 controls with IDDM without diabetic nephropathy were interviewed about their previous and current smoking habits
Freedman et al., J Am Soc Nephrol 1993 (Diabetes Mellitus, Type 1...) : Racial variation in human leukocyte antigen frequency in insulin dependent diabetic nephropathy
Gault et al., Nephron 1996 (Cardiovascular Diseases...) : It has been considered unlikely that patients with insulin dependent diabetes and diabetic nephropathy with nephrotic range proteinuria can substantially reduce proteinuria and continue for many years without further loss of renal function
Garza et al., Am J Nephrol 1997 (Diabetes Mellitus, Type 2...) : These data suggest that ethnicity and sex related factors may be as important as blood pressure and glycemic control during the course of non-insulin dependent diabetic nephropathy
Tarnow et al., Ugeskr Laeger 1998 (Chromosome Deletion...) : We performed an observational follow-up study of 35 patients with insulin dependent diabetes and diabetic nephropathy