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ABCB1 — PLEC

Text-mined interactions from Literome

Cheng et al., Drug Metab Dispos 2006 : In duodenum, PCN increased Abca1 and Mdr1a mRNA expression in WT mice, but not in PXR-null mice ... In jejunum and ileum, PCN increased Mdr1a and Mrp2 mRNA, but decreased Cnt2 mRNA in WT mice, but none of these transporters was altered when PCN was administered to PXR-null mice
Martin et al., Acta Pharmacol Sin 2010 (Carcinoma, Hepatocellular...) : Dexamethasone ( DEX ) and pregnenolone 16alpha carbonitrile (PCN) significantly induced PXR, CYP3A9, ABCB1a and ABCB1b