Gene interactions and pathways from curated databases and text-mining

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POLR2E — TAT

Text-mined interactions from Literome

Liu et al., Virology 1999 : Human immunodeficiency virus type 1 Tat dependent activation of an arrested RNA polymerase II elongation complex
Stevens et al., Med Res Rev 2006 : The Tat-TAR dependent phosphorylation of RNA polymerase II plays an important role in transcriptional elongation as well as in other post-transcriptional events
Lau et al., Cell cycle (Georgetown, Tex.) 2009 : Hexamethylene bis-acetamide inducible protein 1 ( HEXIM1 ) is an inhibitor of the positive transcription elongation factor b ( P-TEFb ), which controls RNA polymerase II transcription and human immunodeficiency virus Tat transactivation
Ernest et al., J Biol Chem 1978 : The RNA polymerase II inhibitor, alpha-amanitin, completely blocked the dibutyryl cyclic AMP mediated increase in tyrosine aminotransferase mRNA activity
Wu-Baer et al., Proc Natl Acad Sci U S A 1995 : Specific binding of RNA polymerase II to the human immunodeficiency virus trans activating region RNA is regulated by cellular cofactors and Tat
Mavankal et al., Proc Natl Acad Sci U S A 1996 : These studies are consistent with the model that RNA polymerase II is a cellular target for Tat resulting in Tat mediated increases in transcriptional elongation from the HIV long terminal repeat
Pagtakhan et al., Virology 1997 : We suggest that these interactions, rather than direct Tat/Sp1 binding, result in highly processive RNA polymerase II complexes and full-length viral transcripts