UCSC Genome Browser Gene Interaction Graph

JavaScript is disabled in your web browser

You must have JavaScript enabled in your web browser to use the Genome Browser

Gene interactions and pathways from curated databases and text-mining

◀ Back to EDN1

CDC42 — EDN1

Pathways - manually collected, often from reviews:

NCI Pathway Database Endothelins: ETA receptor/Endothelin-1/G12/GTP complex (EDNRA-EDN1-GNA12) → Rho family GTPase (RAC1/RHOA/CDC42) (modification, activates)
Gohla et al., J Biol Chem 1999, Nishida et al., J Biol Chem 2007
NCI Pathway Database Endothelins: ETA receptor/Endothelin-1/G12/GTP complex (EDNRA-EDN1-GNA12) → Rho Family GTPase-active (RHOA/CDC42/RAC1) (modification, activates)
Gohla et al., J Biol Chem 1999, Nishida et al., J Biol Chem 2007

Text-mined interactions from Literome

Chahdi et al., J Biol Chem 2005 : Endothelin 1 induces beta 1Pix translocation and Cdc42 activation via protein kinase A-dependent pathway
Chahdi et al., Experimental biology and medicine (Maywood, N.J.) 2006 (Cell Transformation, Viral) : Endothelin 1 stimulates beta1Pix dependent activation of Cdc42 through the G ( salpha ) pathway