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EPO — FOXO3
Text-mined interactions from Literome
Chong et al., Br J Pharmacol 2007
:
Furthermore,
EPO maintained the inhibitory phosphorylation and integrity of the ` pro-apoptotic ' transcription factor FOXO3a,
promoted the binding of
FOXO3a to 14-3-3 protein and regulated the intracellular trafficking of FOXO3a
Chong et al., Curr Neurovasc Res 2011
(Diabetes Mellitus, Experimental...) :
Subsequently, we show that
EPO requires modulation of both Wnt1 and
FoxO3a to oversee mitochondrial membrane depolarization, cytochrome c release, and caspase activation during elevated D-glucose