Gene interactions and pathways from curated databases and text-mining

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EPO — FOXO3

Text-mined interactions from Literome

Chong et al., Br J Pharmacol 2007 : Furthermore, EPO maintained the inhibitory phosphorylation and integrity of the ` pro-apoptotic ' transcription factor FOXO3a, promoted the binding of FOXO3a to 14-3-3 protein and regulated the intracellular trafficking of FOXO3a
Chong et al., Curr Neurovasc Res 2011 (Diabetes Mellitus, Experimental...) : Subsequently, we show that EPO requires modulation of both Wnt1 and FoxO3a to oversee mitochondrial membrane depolarization, cytochrome c release, and caspase activation during elevated D-glucose