Gene interactions and pathways from curated databases and text-mining

◀ Back to EGF

EGF — FASLG

Text-mined interactions from Literome

Eberle et al., Apoptosis 2007 : FRET-studies in mouse embryonic fibroblasts, which in contrast to Huh7 express endogenous CD95, revealed that EGF , but not CD95L induced EGFR-homomerization, whereas CD95 ligand , but not EGF resulted in EGFR/CD95-heteromerization
Fan et al., Stem Cells 2007 : By sustaining mitogen activated protein kinase kinase-extracellular regulated kinase signaling, tethered EGF increases the contact of MSC with an otherwise moderately adhesive synthetic polymer and confers resistance to cell death induced by the proinflammatory cytokine, Fas ligand
Rodrigues et al., Cell Transplant 2012 : In parallel, FasL induces upregulation of the uncoupling protein UCP2, the main uncoupling protein in MSCs, which is not abrogated by EGF ; however, the production of ROS is followed by a delayed apoptotic cell death despite moderation by UCP2