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Lukivskaya et al., Eur J Clin Invest 2008
(Disease Models, Animal...) :
Both NOS inhibitors up-regulated procollagen alpha1 ( I ), MMP-13, TIMP-1 and PAI-1 mRNA expression
Makarova et al., J Biol Chem 2011
(Acute Lung Injury...) :
Two-chain uPA ( 1-20 nM ) and uPA-PAI-1 induced phosphorylation of endothelial NOS-Ser ( 1177 ) in PMVECs, which was followed by generation of NO and the nitrosylation and dissociation of ß-catenin from VE-cadherin