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DYRK1A — NEUROD4

Text-mined interactions from Literome

Yabut et al., J Neurosci 2010 : Dyrk1A overexpression inhibits proliferation and induces premature neuronal differentiation of neural progenitor cells ... We found that Dyrk1A overexpression inhibits neural cell proliferation and promotes premature neuronal differentiation in the developing cerebral cortex without affecting cell fate and layer positioning
Hämmerle et al., Development 2011 : Furthermore, we found that MNB/DYRK1A suppressed NOTCH signaling, counteracted the pro-proliferative action of the NOTCH intracellular domain ( NICD ), stimulated Delta1 expression and was required for the neuronal differentiation induced by the decrease in NOTCH signaling