◀ Back to ICAM1
ICAM1 — IL1RN
Text-mined interactions from Literome
Yang et al., Brain Res Mol Brain Res 1999
(Arterial Occlusive Diseases...) :
Since interleukin-1 can up-regulate intercellular adhesion molecules in endothelium, the present study was designed to determine whether overexpression of the
IL-1ra can
reduce the expression of
intercellular adhesion molecule-1 ( ICAM-1 ) after ischemic injury
Zhu et al., Invest Ophthalmol Vis Sci 1999
(Corneal Neovascularization) :
IL-1ra induced suppression of
ICAM-1 expression was accompanied by a profound decrease in corneal leukocytic infiltration by 44.6 % at day 1 ( P < 0.003 ), 71.8 % at day 3 ( P < 0.001 ), 60.1 % at day 7 ( P < 0.001 ), and 63.8 % at day 14 ( P < 0.001 ), compared with control corneas
Wirjatijasa et al., J Neurosci Res 2002
:
In summary, we demonstrate that IL-4, IL-10, and
IL-1-ra induce microglial ramification and
reduce ICAM-1-expression , whereas the secretion of proinflammatory cytokines is not prevented
Liu et al., Zhonghua Yan Ke Za Zhi 2003
(Graves Disease) :
[ The inhibition
effect of
interleukin-1 receptor antagonist on interleukin-1 alpha induced
intercellular adhesion molecule-1 expression on orbital fibroblasts and adhesion of peripheral blood mononuclear cells ] ... The aim was to identify whether
interleukin-1 receptor antagonist ( IL-1ra )
inhibits interleukin-1 alpha (IL-1 alpha) induced
intercellular adhesion molecule-1 ( ICAM-1 ) expression on cultured orbital fibroblasts, and adhesion of peripheral blood mononuclear cells ( PBMC ) to orbital fibroblasts, and to investigate the clinical application potential of IL-1ra in the treatment of Graves ' ophthalmopathy ( GO ) ...
IL-1ra inhibits IL-1 alpha induced
ICAM-1 expression in cultured orbital fibroblasts both from GO patients and controls ; IL-1ra inhibits IL-1 alpha induced adhesion of PBMC to orbital fibroblasts in a concentration and time dependent manner ...
IL-1ra inhibits IL-1 alpha induced
ICAM-1 expression in cultured orbital fibroblasts and the adhesion of PBMC to fibroblasts
Lee et al., Infect Immun 2005
(Periodontitis) :
The increased
ICAM-1 and IL-8 expression in the THP-1 cells obtained with rMsps was not inhibited in the
presence of the
IL-1 receptor antagonist (IL-1ra) , a natural inhibitor of IL-1
Salkind et al., J Clin Invest 1991
:
These studies were undertaken to investigate
effects of exposure and resultant net
IL-1 inhibitor activity on the expression of the
intercellular adhesion molecule-1 ( ICAM-1 ), and its ligand the lymphocyte function associated antigen ( LFA-1 )
Fischer et al., Immunol Cell Biol 2010
(Vascular Diseases) :
Interestingly, overexpression of
icIL-1ra also
inhibited TNF induced upregulation of
ICAM-1
Hong et al., J Neuroimmunol 1993
(Neuroblastoma) :
The
effects of a recombinant human
interleukin-1 (IL-1) receptor antagonist ( IL-1ra ) and a recombinant human soluble IL-1 receptor ( sIL-1R ) on cytokine induced intercellular adhesion molecule-1 (
ICAM-1 ) expression in a human glioblastoma cell line and a neuroblastoma cell line were determined ...
ICAM-1 expression induced by IL-1 beta, rabbit IL-1 beta 208-240 and human IL-1 beta 208-240 was
blocked by the
IL-1ra , while TNF alpha- and IFN gamma induced ICAM-1 expression were not
Burke-Gaffney et al., Am J Physiol 1996
:
LPS induced
ICAM-1 expression was not
inhibited by
interleukin-1 (IL-1) receptor antagonist ( 0.01-100 micrograms/ml )