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FAS — PPP2CA

Text-mined interactions from Literome

Chalfant et al., J Biol Chem 2001 : The serine/threonine protein phosphatase inhibitor, calyculin A, but not the PP2A-specific inhibitor, okadaic acid, inhibited both FAS- and ceramide induced dephosphorylation of SR proteins
Park et al., Cancer Res 2010 (Gastrointestinal Neoplasms) : ROS generation, CD95 activation , and cell killing was also blocked by quenching of induced Ca ( 2+ ) levels or by inhibition of PP2A
Kwan et al., Eur J Nutr 2013 : Inhibition of PP2A by okadaic acid, knockdown of DNA-PK by siRNA or inhibition of DNA-PK by specific DNA-PK inhibitors curtailed the FFA induced upregulations of the SREBP1 mRNA expression and the nuclear active SREBP1 protein expression, and reduced FFA induced upregulation of FAS promoter transcriptional activity and lipid accumulation