◀ Back to CD40
CD40 — IL15
Text-mined interactions from Literome
Zanussi et al., Scand J Immunol 1999
(HIV Infections) :
On the contrary,
CD40 ligation did not
induce IL-15 production by PBMCs. Surface CD14 was down modulated, as a consequence of CD40 stimulation, on monocytes from healthy controls but not on monocytes from HIV positive patients
Bartholomé et al., J Interferon Cytokine Res 1999
:
IFN-beta interferes with the differentiation of dendritic cells from peripheral blood mononuclear cells : selective inhibition of
CD40 dependent
interleukin-12 secretion
Kitagawa et al., Arthritis Rheum 1999
(Arthritis, Rheumatoid) :
Differential
regulation of rheumatoid synovial cell
interleukin-12 production by tumor necrosis factor alpha and
CD40 signals
Muraille et al., Blood 1999
:
Anti-CD3epsilon treatment was found to induce a selective deficiency in the ability of spleen cells to produce bioactive
interleukin-12 in
response to
CD40 stimulation
Sugiura et al., J Immunol 2000
(Dermatomyositis...) :
Increased CD40 expression on muscle cells of polymyositis and dermatomyositis :
role of
CD40-CD40 ligand interaction in IL-6, IL-8,
IL-15 , and monocyte chemoattractant protein-1 production
Weiler et al., J Am Soc Nephrol 2001
:
CD40 ligation
enhances IL-15 production by tubular epithelial cells ... The
effect of
CD40 ligation on
IL-15 production in human tubular epithelial cells (TEC) was investigated
Basok et al., J Am Soc Nephrol 2001
:
CD40 ligation
induced IL-15 production by HPMC and was additive to IFNgamma stimulation
Cattaruzza et al., J Biol Chem 2003
:
Interleukin-10 induction of nitric-oxide synthase expression attenuates
CD40 mediated
interleukin-12 synthesis in human endothelial cells
Pinzon-Charry et al., Neoplasia (New York, N.Y.) 2005
(Adenocarcinoma...) :
Importantly, despite DR ( + ) IC 's poor responsiveness to inflammatory factors, in samples from healthy volunteers and breast cancer patients,
CD40 ligation
induced phenotypic maturation and
interleukin 12 secretion, in turn generating more efficient T-cell responses
Danese et al., Gut 2007
(Colitis...) :
Engagement of
CD40 on HIFs
promoted the release of vascular endothelial growth factor ( VEGF ),
interleukin-8 (IL-8) and hepatocyte growth factor (HGF)
Bose et al., Hum Immunol 2007
(Carcinoma, Squamous Cell...) :
Natural killer cell mediated cytotoxicity of tumor cells initiated by neem leaf preparation is associated with
CD40-CD40L mediated endogenous production of
interleukin-12
Zhang et al., J Immunol 2012
(Neoplasms, Experimental) :
These findings support the view that
anti-CD40 mediated augmented
IL-15Ra expression was critical in IL-15 associated sustained remissions observed in TRAMP-C2 tumor bearing mice receiving combination therapy
Kennedy et al., Eur J Immunol 1996
:
CD40/CD40 ligand interactions are
required for T cell dependent production of
interleukin-12 by mouse macrophages
Cella et al., J Exp Med 1996
:
Ligation of
CD40 on dendritic cells
triggers production of high levels of
interleukin-12 and enhances T cell stimulatory capacity : T-T help via APC activation
Yoshimoto et al., Eur J Immunol 1997
:
Induction of
interleukin-12 p40 transcript by
CD40 ligation via activation of nuclear factor-kappaB
Séguin et al., J Infect Dis 1999
:
Sensitized lymphocytes and
CD40 ligation
augment interleukin-12 production by human dendritic cells in response to Toxoplasma gondii