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IFNG — TNFRSF1A
Text-mined interactions from Literome
Horie et al., Exp Hematol 1999
(Leukemia, Myeloid, Acute) :
In conclusion, TNF induced apoptosis was mediated preferentially by
TNFR1 , and the anti-apoptotic effect of
IFN-gamma was
result from up-regulated TNFR2 in EoL-1 cell line
Wong et al., J Immunol 1992
:
We have found that
anti-TNF-R1 , but not anti-TNF-R2, Ab trigger antiviral activity in human hepatoma Hep-G2 cells and
enhance the antiviral activity of
IFN-gamma in human lung fibroblast A549 cells
Buntinx et al., J Neurosci Res 2004
:
In addition to direct cytotoxic effects,
IFN-gamma and TNF-alpha also
enhance the expression of Fas,
TNFR1 , and MHC class I molecules in both cell lines
Bode et al., J Biol Chem 2006
(Genetic Predisposition to Disease...) :
However,
IFNgamma up-regulated
TNFR1 expression and amplified TNFalpha induced protein leakage
Solarewicz-Madejek et al., Clin Exp Allergy 2009
(Asthma...) :
IFN-gamma and TNF-alpha
up-regulated TNFR1 , TNFR2, Fas and membrane FasL on SMC
Agresti et al., Eur J Neurosci 1998
:
Following the exposure of oligodendrocytes to IFN-gamma,
TNF-R1 expression was transcriptionally
induced by the binding of signal transducer and activator of transcription ( STAT-1 ) homodimers to the
IFN-gamma activated site ( GAS ) present in the gene promoter
Chan et al., J Immunol 1999
:
Collectively, these findings support the involvement of p46 JNK/SAPK and its upstream kinases in regulating the induction of iNOS following ligation of the TNF-alpha receptor
CD120a ( p55 ) in the
presence of
IFN-gamma