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FGF2 — SOX9

Text-mined interactions from Literome

Murakami et al., Proc Natl Acad Sci U S A 2000 (MAP Kinase Signaling System) : The increase in Sox9 levels induced by FGF2 was inhibited by a specific mitogen activated protein kinase kinase ( MAPKK ) /mitogen activated protein kinase/ERK kinase ( MEK ) inhibitor U0126 in primary chondrocytes
Petiot et al., Dev Dyn 2002 (Craniosynostoses) : This closely resembled the response of nonelectroporated neural crest cells to FGF2 in vitro : 10 ng/ml induces chondrogenesis, Sox9, Col2a1, and osteopontin expression, whereas 1 ng/ml FGF2 enhances cell survival and Sox9 and Col2a1 expression, but never induces chondrogenesis or osteopontin expression
Handorf et al., PloS one 2011 : Further, we show using flow cytometry that FGF-2 increased Sox9 protein levels per cell in proliferating and non proliferating hMSCs, strongly suggesting that FGF-2 primes hMSCs for subsequent CG by regulating Sox9
Yardley et al., Dev Biol 2012 : We report that in response to FGF the non-neural ectoderm can ectopically express several early neural crest markers ( Pax7, Msx1, Dlx5, Sox9 , FoxD3, Snail2, and Sox10 )