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MAPK1 — RB1
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Manabe et al., J Biol Chem 1999
:
Inclusion of the EDA segment potentiated the ability of FN to induce expression of cyclin D1, hyperphosphorylation of
pRb , and
activation of mitogen activated protein kinase
extracellular signal regulated kinase 2 ( ERK2 )
von Willebrand et al., Cancer Res 2003
(MAP Kinase Signaling System...) :
Thus, inhibition of melanoma cell proliferation by AG1024 is mediated by inhibition of
mitogen activated protein kinase/extracellular signal regulated kinase 2 signaling and
activation of
pRb by a mechanism involving protein degradation ... Thus, inhibition of melanoma cell proliferation by AG1024 is mediated by inhibition of mitogen activated protein
kinase/extracellular signal regulated kinase 2 signaling and
activation of
pRb by a mechanism involving protein degradation
Song et al., Yao Xue Xue Bao 2008
:
[ JNK/p38
MAPK involves in ginsenoside
Rb1 attenuating beta-amyloid peptide ( 25-35 ) -induced tau protein hyperphosphorylation in embryo rat cortical neurons ]
Yeste-Velasco et al., Neurochem Int 2009
(Retinal Neoplasms...) :
In conclusion, these results suggest that
p38MAPK converged with the cell cycle in S/K deprivation
induced apoptosis through
pRb phosphorylation