Gene interactions and pathways from curated databases and text-mining

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CCND1 — PRKACG

Text-mined interactions from Literome

Lamb et al., Mol Cell Biol 2000 (Breast Neoplasms) : Further, we show that culture of MCF-7 cells on a cellular substratum of murine preadipocytes also enhanced the functional interaction between cyclin D1 and ER in a PKA dependent manner
Mantovani et al., J Clin Endocrinol Metab 2005 (Adenoma...) : Moreover, in group 2, PKA blockade by the specific inhibitor PKI increased cyclin D1 expression ( 96 +/- 25 % over basal ) and ERK1/2 activity ( 116 +/- 28 % over basal )
Fassett et al., Mol Biol Cell 2006 : PKA inhibition also restored ERK activation, cyclin D1 expression and G1-S progression on collagen gel, but had no effect on cells adherent to collagen film
Friedrichsen et al., J Endocrinol 2006 : We conclude that incretin induced beta-cell replication is dependent on cAMP/PKA , p42 MAPK and PI3K activities, which may involve transcriptional induction of cyclin D1
Taurin et al., Am J Physiol Cell Physiol 2008 : Using the PKA inhibitor PKI or dominant negative TCF-4 mutant, we show that ATP induced cyclin D1 promoter activation, cyclin D1 protein expression, and proliferation of VSMC are all dependent on PKA and TCF activities