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ABCA8 — APOA1
Text-mined interactions from Literome
Haidar et al., J Biol Chem 2004
(Tangier Disease) :
Naturally occurring mutations of ABCA1 associated with Tangier disease ( C1477R, 2203X, and 2145X ) severely reduced
apoA-I mediated cAMP production,
ABCA1 phosphorylation, ( 125 ) I-apoA-I binding, and lipid efflux, without affecting forskolin mediated cAMP elevation
Fukuda et al., J Lipid Res 2008
:
These results suggest the following new scenario of nascent HDL formation
: ABCA1 , which colocalizes with apoA-I in acidic intracellular compartments, including the Golgi and endosome, increases acidity at the membrane surface on the luminal side by PS translocase activity and
causes apoA-I to form nascent HDL