Gene interactions and pathways from curated databases and text-mining

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IL16 — IL18

Text-mined interactions from Literome

Takahashi et al., Antimicrob Agents Chemother 2005 : In addition, ciprofloxacin suppressed the interleukin-18 induced production of tumor necrosis factor alpha, gamma interferon, and interleukin-12 in peripheral blood mononuclear cells by inhibiting the expression of intercellular adhesion molecule 1, B7.1, B7.2, and CD40 on monocytes, and this effect could be reversed by the addition of indomethacin or NS398
El Bassam et al., Immunology 2006 (Asthma...) : To evaluate whether the modulatory effect of IL-16 on cytokine synthesis was mediated by interferon-gamma (IFN-gamma), IL-10, IL-12 or IL-18 , allergen stimulated PBMC were cultured in presence of IL-16 and neutralizing concentrations of relevant antibodies