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STMN1 — TP53

Text-mined interactions from Literome

Johnsen et al., Int J Cancer 2000 : p53 mediated negative regulation of stathmin/Op18 expression is associated with G ( 2 ) /M cell-cycle arrest ... Evidence that p53 is directly or indirectly involved in negative regulation of stathmin/Op18 expression includes the following : ( i ) p53 mediated growth inhibition is associated with repression of stathmin/Op18 expression following serum stimulation, ( ii ) reporter gene assays revealed p53 mediated repression of stathmin/Op18 promoter activity and ( iii ) constitutive over-expression of stathmin/Op18 bypasses a p53 mediated G ( 2 ) /M arrest in the cell cycle ... These results suggest that p53 mediated negative regulation of stathmin/Op18 plays an important role in cell-cycle control
Alli et al., Cancer Res 2002 (Breast Neoplasms) : Stathmin is a p53 regulated protein known to influence microtubule dynamics
Sonego et al., EMBO Mol Med 2013 (Ovarian Neoplasms) : Stathmin regulates mutant p53 stability and transcriptional activity in ovarian cancer