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CCND1 — NOTCH1
Text-mined interactions from Literome
Ronchini et al., Mol Cell Biol 2001
:
Using this inducible system, we show that
Notch ( ic )
activates transcription of the
cyclin D1 gene with rapid kinetics ... Upregulation of
cyclin D1 and
activation of CDK2 by
Notch ( ic ) result in the promotion of S-phase entry
Stahl et al., Cancer Res 2006
(Cell Transformation, Neoplastic) :
To determine if
Notch1 induced
cyclin D1 expression in RKE-ER-N ( ic ) cells plays a direct role in transformation, cyclin D1 up-regulation was inhibited using a cyclin D1 antisense cDNA
Lindsay et al., Clinical and translational science 2008
(Breast Neoplasms) :
ErbB2 induced cyclin D1 and cyclin D1 expression was suficient to induce Notch1 activity, and conversely, genetic deletion of Notch1 in mammary epithelial cells using foxed Notch ( Notch ( fl/fl ) ) mice demonstrated that
cyclin D1 is
induced by
Notch1
Zhang et al., Life Sci 2013
(Asthma...) :
In the present study, we determined whether Phosphoinositide 3-kinase (PI3K) and
Notch signal pathways are
involved in the expression of
cyclinD1 , cyclinA and p27kip1 which were key molecules in controlling cell cycling from CD4 ( + ) T lymphocyte in animal model of asthma