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FGFR3 — GPI

Text-mined interactions from Literome

Okada et al., Pflugers Arch 1991 : The increase in pHi induced by ACh or ionomycin was not inhibited by the protein kinase C inhibitors staurosporine ( 10 nM ) and 1- ( 5-isoquinolinesulfonyl ) -1-methylpiperazine ( 50 mumol/l ) ... In Ca ( 2+ ) -free solution with 50 mumol/l 8- ( diethylamino ) -octyl-3,4,5-trimethoxybenzoate, the ACh induced rise in both pHi and cytosolic Ca2+ concentration was suppressed
Martorell et al., Cardiovasc Res 2009 : Ovariectomy increased the ACh induced TXA ( 2 ), PGI ( 2 ), and PGE ( 2 ) release and the contractile responses induced by exogenous TXA ( 2 ), PGF ( 2alpha ), or PGE ( 2 ), while it decreased the PGI ( 2 ) -induced vasodilator response
Saito et al., J Membr Biol 1988 : Stimulation with 1 microM acetylcholine (ACh) caused a transient, small decrease and then a sustained increase in pHi ... Pretreatment with DIDS ( 0.2 mM ) did not change the pHi of the nonstimulated conditions ; however, it significantly enhanced the increase in pHi induced by ACh
Lundy et al., Eur J Pharmacol 1988 : omega-CgTx ( 0.01-1.0 microM ) reduced the electrically stimulated GPI twitch height, failed to modify exogenously applied acetylcholine (ACh) contractions, and inhibited Ca2+ dependent KCl stimulated ACh release as measured by chemiluminescence
Peredo et al., Prostaglandins Leukot Essent Fatty Acids 1993 : ACh , in stimulating muscarinic receptors, induces the production and release of PGI2 from endothelium and TXA2 from vascular smooth muscle when the endothelium is absent
Jeremy et al., Br J Pharmacol 1993 (Body Weight...) : These data indicate that : ( i ) reduced PGI2 synthesis coupled to adrenoceptors and AII receptors in the aortae of diabetic rats may be due to diminished PKC activity and not to changes in receptor density and/or affinity, Ca2+ stores, PLA2, cyclo-oxygenase or PGI2 synthase ; ( ii ) the diametrically opposite effect of DM on ACh stimulated PGI2 synthesis is not due to an increase in PKC activity, but possibly to an increase in muscarine receptor number and/or affinity ; ( iii ) changes in receptor linked PGI2 synthesis are not ubiquitous in experimental DM and may be organ-specific
Kan et al., J Pharmacol Exp Ther 1997 : ACh induced production of PGI2 , measured as immunoreactive 6-keto-PGF1alpha, was enhanced by increasing the extracellular calcium ( Ca++ ) concentration and reduced by Ca++ depletion
Tran Dinh et al., Brain Res 1998 (Subarachnoid Hemorrhage) : Alternatively, in the SAH group constrictor prostaglandins were released in response to HA and ACh in place of PGI2