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IFNG — MTX1

Text-mined interactions from Literome

Morita et al., Scand J Rheumatol 2006 (Arthritis, Rheumatoid) : The effect of MTX on intracellular expression of interferon-gamma (IFN-gamma) and interleukin-4 (IL-4), and cell surface expression of signalling lymphocytic activation molecule ( SLAM ) from freshly isolated peripheral blood mononuclear cells ( PBMCs ), and after in vitro culture with or without MTX, was analysed with flow cytometry in 18 patients with RA and 20 healthy controls
Reiss et al., Arthritis Rheum 2008 (Atherosclerosis) : MTX also prevented NS398 and IFNgamma from increasing transformation of lipid-laden THP-1 macrophages into foam cells
Li et al., Zhongguo Zhong Xi Yi Jie He Za Zhi 2011 : To observe the effect of Shenghua Decoction in reversing IFN-gamma inhibition induced by methotrexate (MTX) ... Shenghua Decoction showed reversing effect on MTX induced IFN-gamma inhibition by promoting the differentiation of IFN-gamma+Th1 subpopulation and up-regulating IFN-gamma expression, thus promoting the feto-maternal immunological rejection
Neurath et al., Clin Exp Immunol 1999 (Arthritis, Experimental) : The role of TNF in MTX mediated effects on cytokine production was further underlined by the finding that MTX effects on IFN-gamma production were augmented in TNF-transgenic mice but abrogated in mice in which the TNF-alpha gene had been inactivated by homologous recombination