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CXCL10 — IL8
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Sebastiani et al., Arch Dermatol Res 2002
(Dermatitis, Contact) :
Chemokines are produced in a coordinated and sequential manner, with
IL-8 and RANTES induced by TNF-alpha during early stages, and MCP-1,
IP-10 , Mig, I-TAC, I-309 and MDC
induced by IFN-gamma during later stages
van Zandbergen et al., Infect Immun 2002
:
In addition, we found that leishmanial contact induced the release of
interleukin-8 (IL-8) and
inhibited the production of gamma
interferon-inducible protein 10 (IP-10) by PMN
Laine et al., Biochem Biophys Res Commun 2007
:
Palmitic acid ( PA ), the predominant saturated FFA released from adipose tissue, but not unsaturated FFA,
induced an approximately 6-fold ( p < 0.05 ) increase in
IP-10 gene expression ( and 2- to 4-fold increases in
IL-8 , MCP-1, COX-2, and MIG )
Hosokawa et al., J Periodontal Res 2009
(Periodontitis) :
However,
interleukin-4 and interleukin-13
inhibited CXCL10 production by interferon-gamma stimulated or tumor necrosis factor-alpha-stimulated-human gingival fibroblasts ... On the other hand,
interleukin-17A and interleukin-22 enhanced CXCL10 production by human gingival fibroblasts treated with interferon-gamma and
inhibited CXCL10 production by tumor necrosis factor-alpha stimulated human gingival fibroblasts
Lai et al., Int J Gynecol Cancer 2011
(Genital Neoplasms, Female...) :
Similar treatment in HeLa cells caused increases in the mRNA levels of CCL2,
CXCL2 , IL-6, and IL-8, and in SKOV3 cells, mRNA levels of CCL2, CCL20, CXCL1, CXCL2, IL-6, and
IL-8 increased
Tousi et al., Neurosci Lett 2012
(Parkinson Disease) :
a-Synuclein potentiates
interleukin-1ß induced
CXCL10 expression in human A172 astrocytoma cells
Lee et al., Eur Respir J 2012
(Inflammation...) :
NRF knockdown
enhanced IL-8/CXCL8 production in normal PBMCs, whilst NRF overexpression attenuated
IL-8/CXCL8 production