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FGF2 — S100A8

Text-mined interactions from Literome

Rahimi et al., FEBS J 2005 : FGF-2 , IL-1beta and TGF-beta regulate fibroblast expression of S100A8 ... Endotoxin ( LPS ), interferon gamma (IFNgamma), tumour-necrosis factor (TNF) and TGF-beta did not induce the S100A8 gene in murine fibroblasts whereas FGF-2 induced mRNA maximally after 12 h ... S100A8 mRNA induction by FGF-2 and IL-1beta was partially dependent on the mitogen-activated-protein-kinase pathway and dependent on new protein synthesis ... Up-regulation of S100A8 by FGF-2/IL-1beta , down-regulation by TGF-beta, and its time dependent expression in wound fibroblasts suggest a role in fibroblast differentiation at sites of inflammation and repair
Katoh et al., Int J Oncol 2006 (Stomach Neoplasms...) : Helicobacter pylori, a causative pathogen for peptic ulcer diseases, chronic atrophic gastritis and gastric cancer, injects bacterial proteins into gastric epithelial cells by using Type IV secretion system, which leads to FGF signaling activation through FGF2 upregulation as well as CagA dependent SHP2 activation