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NGF — RAC2
Text-mined interactions from Literome
Chakrabarti et al., Mol Cell Biol 2005
:
Furthermore, elevated Kalirin expression resulted in catalytic activation of TrkA, as demonstrated by in vitro kinase assays and increased
NGF stimulated cellular activation of
Rac , Mek, and CREB
Noga et al., Clin Exp Allergy 2007
(Hypersensitivity) :
NGF led to decreased RhoA and increased
Rac activation, while BDNF affected RhoA and Rac activity in a reciprocal fashion
Talebian et al., J Mol Neurosci 2013
:
Moreover, we find that H-Ras over-expression rescues the loss of neurite outgrowth observed with a Rac minus mutant and that RasGrf1 differentially stimulates
NGF dependent
activation of
Rac or Ras, depending on cell type