Gene interactions and pathways from curated databases and text-mining

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MMP2 — SMAD2

Text-mined interactions from Literome

Mao et al., Yi Chuan Xue Bao 2005 : [ SMAD3 inhibits the expression of MMP-2 in mouse embryonic fibroblasts ]
Lin et al., Frontiers in bioscience : a journal and virtual library 2006 : Involvement of SMAD4, but not of SMAD2 , in transforming growth factor-beta1 induced trophoblast expression of matrix metalloproteinase-2 ... In the present study, we examined the possible role of Smad4 and Smad2 in transforming growth factor (TGF)-beta1 induced MMP-2 expression, using the well established invasive extravillous trophoblast cell line HTR-8/SVneo ... These findings suggest that Smad4, but not Smad2 , mediates TGF-beta1 induced MMP-2 expression in invasive extravillous trophoblasts
Phanish et al., Biochem J 2006 : TGFbeta1 induced increases in CTGF and decreases in E-cadherin expression were Smad3 dependent, whereas increases in MMP-2 expression were Smad2 dependent