Chu et al., J Immunol 2004
:
Finally, we demonstrate that, in primary T cells, dominant negative PAK2 prevented anti-CD3/CD28 induced IL-2 production, and TCR induced CD40 ligand expression, both key functions of activated T cells
Yamashita et al., Anticancer Res 1986
:
These findings suggest the possibility that PGE2 regulates PAK activity in PBL by inhibiting the production of IL-2 by activated T cells