Gene interactions and pathways from curated databases and text-mining

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EGFR — ESR2

Text-mined interactions from Literome

Johnston et al., Clin Cancer Res 2006 (Breast Neoplasms) : The increasing recognition of the roles of epidermal growth factor receptor (EGFR) and human EGFR2 in cross-talk activation of estrogen receptor signaling has led to studies aimed at identifying whether small-molecule tyrosine kinase inhibitors targeted against these receptors give additive or synergistic effects when combined with endocrine agents
Burga et al., Breast Cancer Res 2011 (Cell Transformation, Neoplastic...) : Loss of BRCA1 leads to an increase in epidermal growth factor receptor expression in mammary epithelial cells, and epidermal growth factor receptor inhibition prevents estrogen receptor negative cancers in BRCA1-mutant mice
Fitzpatrick et al., Cancer Res 1984 (Breast Neoplasms) : Epidermal growth factor receptors ( EGF-R ) were measured in a series of breast tumors to determine what percentage of breast tumors express EGF-R and whether EGF-R was independent of expression of estrogen receptor and progestin receptor
Sheikh et al., J Cell Biochem 1994 (Breast Neoplasms...) : Recent studies suggest that the epidermal growth factor-receptor does not regulate the estrogen receptor gene expression ... Whether the estrogen receptor regulates the epidermal growth factor-receptor gene expression is not known
deFazio et al., Cell Growth Differ 1997 (Breast Neoplasms) : Antisense estrogen receptor RNA expression increases epidermal growth factor receptor gene expression in breast cancer cells