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ITIH4 — MAPK14
Text-mined interactions from Literome
Kinet et al., Blood 2002
(MAP Kinase Signaling System) :
Here, we report that
gp120 binding
resulted in activation of the mitogen activated protein kinase (
MAPK ) in CD4 ( + ) lymphocytes prestimulated through their T-cell receptor ( TCR ) ... Nevertheless, like peripheral blood lymphocytes,
MAPK recruitment was
induced by
gp120 in UC T cells following TCR prestimulation
Kapasi et al., Mol Med 2002
(MAP Kinase Signaling System) :
In addition,
gp120 promoted tubular cell p38
MAPK phosphorylation in a time- and dose- dependent manner
Badr et al., J Immunol 2005
(HIV Infections) :
Unlike CXCL12,
gp120 did not
induce the activation of phospholipase Cbeta3 and PI3K downstream from CXCR4, whereas p38
MAPK activation was observed
Bruno et al., Gut 2010
(HIV Infections...) :
gp120 also
induced activation of nuclear factor-kappaB (NF-kappaB) and p38 (
MAPK )
Kuang et al., Eur J Immunol 2012
(HIV Infections) :
Here, we show that NHERF1 can associate with CCR5, and promote activation of the
gp120 induced
MAPK/ERK , focal adhesion kinase and RhoA ( Ras homolog gene family member A ) signaling pathways