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PCNA — ROCK1
Text-mined interactions from Literome
Croft et al., Mol Cell Biol 2006
(MAP Kinase Signaling System) :
The Rho GTPase effector
ROCK regulates cyclin A,
cyclin D1, and p27Kip1 levels by distinct mechanisms
Chen et al., Invest Ophthalmol Vis Sci 2008
:
ROCK signaling is
involved in cell cycle progression in RCECs, possibly by upregulation of
cyclin-D1 and -D3 and CDK4, -6, and -2 ; nuclear translocation of CDK2 and cyclin-E ; and downregulation of p27 ( Kip1 )
Li et al., Zhonghua Xin Xue Guan Bing Za Zhi 2011
(Hypertension, Pulmonary) :
Rosuvastatin also inhibited
PCNA expression of SMC ( P < 0.01 ), restored eNOS expression of EC ( P < 0.05 ) and
inhibited ROCK-1 mRNA expressions in lung tissue ( P < 0.05 )