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CD3D — IL15
Text-mined interactions from Literome
Matthys et al., Clin Exp Immunol 2002
:
These data demonstrate that systemic IL-15 exerts anti-apoptotic activity on immature T cells and establish a regulatory mechanism whereby
TCR/CD3 engagement
induces IL-15 expression via an IFN-gamma dependent pathway
Mustelin et al., Science 1990
:
At doses that inhibited TPK activity and tyrosine phosphorylation of the TCR zeta subunit, but not phospholipase C activity, genistein prevented
TCR-CD3 mediated phospholipase C activation,
interleukin-2 receptor expression, and T cell proliferation