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PLCG1 — RHOA
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
RHOA
—
PLCG1
(physical association, affinity chromatography technology)
Thodeti et al., Biochem J 2002*
-
IRef Biogrid Interaction:
RHOA
—
PLCG1
(direct interaction, pull down)
Thodeti et al., Biochem J 2002*
-
IRef Hprd Interaction:
RHOA
—
PLCG1
(in vitro)
Thodeti et al., Biochem J 2002*
-
IRef Hprd Interaction:
RHOA
—
PLCG1
(in vivo)
Thodeti et al., Biochem J 2002*
-
IRef Ophid Interaction:
RHOA
—
PLCG1
(aggregation, confirmational text mining)
Thodeti et al., Biochem J 2002*
-
IRef Ophid Interaction:
RHOA
—
PLCG1
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
Text-mined interactions from Literome
Thodeti et al., Biochem J 2002
(Calcium Signaling) :
We also found that, within 15 s, activation of
RhoA by LTD4
led to an increased association of RhoA with G-protein betagamma ( Gbetagamma ) and
phospholipase C-gamma1 ( PLC-gamma1 ) in the plasma membrane, as evidenced by the results of co-immunoprecipitation, glutathione S-transferase (GST) pulldown assays, and confocal microscopy
Piechulek et al., J Biol Chem 2005
:
PLCgamma(2), but not
PLCgamma(1) , was markedly
activated in intact cells by constitutively active Rac1 ( G12V ), Rac2 ( G12V ), and Rac3 ( G12V ) but not by Cdc42 ( G12V ) and
RhoA ( G14V )