Gene interactions and pathways from curated databases and text-mining

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MMP9 — TLR9

Text-mined interactions from Literome

Lim et al., FEBS Lett 2006 : The present study examined whether temporal control of toll-like receptor (TLR)-9 by CpG ODN can regulate the expression of matrix metalloproteinase-9 (MMP-9)
West et al., J Cell Biol 2008 : Surprisingly, MMP inhibitors block TLR signaling induced podosome disassembly, although stimulated endocytosis is unaffected, which demonstrates that the two phenomena are not obligatorily coupled
Lee et al., Exp Dermatol 2010 : These findings demonstrate that the activation of TLR2, TLR3 or TLR5 induces the expression of MMP-1 and MMP-9 in human epidermal keratinocytes
Abdulkhalek et al., Cell Signal 2013 (Inflammation) : Tamiflu, specific MMP-9 inhibitor, neuromedin B receptor specific antagonist BIM23127, and the selective inhibitor of whole heterotrimeric G-protein complex BIM-46174 significantly block nucleic acid induced TLR-7 and -9 MyD88 recruitment, NF-?B activation and proinflammatory TNFa and MCP-1 cytokine responses