Gene interactions and pathways from curated databases and text-mining

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ADAM6 — WNT16

Text-mined interactions from Literome

Wei et al., Dev Cell 2010 : ADAM13 upregulates canonical Wnt signaling and early expression of the transcription factor snail2, whereas EfnB1 inhibits the canonical Wnt pathway and snail2 expression
Wei et al., Dev Biol 2012 (Wnt Signaling Pathway) : Roles of ADAM13 regulated Wnt activity in early Xenopus eye development ... We recently found that Xenopus ADAM13 , an ADAM metalloproteinase, is required for activation of canonical Wnt signaling during cranial neural crest (CNC) induction by regulating a novel crosstalk between Wnt and ephrin B ( EfnB ) signaling pathways ( Wei et al., 2010b ) ... Together these data suggest an important role of ADAM13 regulated Wnt activity in eye development in Xenopus