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ADCY9 — REN

Text-mined interactions from Literome

Grünberger et al., Circ Res 2006 : Finally, in isolated perfused mouse kidneys, angiotensin II completely inhibited the stimulation of renin secretion induced by adenylate cyclase activation ( isoproterenol ) but not by membrane permeable cAMP analogs, supporting the conclusion that the suppressive effect of calcium liberators on renin release is mediated by inhibition of adenylate cyclase activity
Everett et al., J Clin Invest 1990 : To investigate whether newborn kidney microvessels and isolated single microvascular cells have the capacity to release renin and/or alter the expression of the renin gene in response to adenylate cyclase stimulation, newborn kidney microvessels were isolated and purified ( 95 % ) using an iron perfusion/enzymatic digestion technique
Pedraza-Chaverrí et al., Life Sci 1986 : Pertussis toxin was used to study the role of adenylate cyclase in the control of renin release
Schricker et al., Am J Physiol 1995 : Renin secretion was stimulated by the adenylate cyclase activator forskolin ( 10 microM ), the NO donor sodium nitroprusside ( SNP, 100 microM ), the calmodulin antagonist calmidazolium ( 10 microM ), by lowering extracellular Ca2+ concentration ([Ca2+]e) with ethylene glycol-bis ( beta-aminoethyl ether ) -N, N,N ', N'-tetraacetic acid ( EGTA ) ( 2 mM ), and by increasing [ Ca2+ ] e from the normal value of 0.5 to 3 mM
Ritthaler et al., Kidney Int 1996 : The adenylate cyclase activator forskolin ( 3 mumol/ liter ) increased renin mRNA levels to 400 % of the controls and this stimulation was dose-dependently attenuated by ET-2 to 250 % of the control value