Gene interactions and pathways from curated databases and text-mining

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AKT3 — SFN

Text-mined interactions from Literome

Moon et al., Cancer Lett 2010 (Carcinoma, Hepatocellular...) : SFN also suppressed the phosphorylation of Akt ( Ser-473 ), thereby inhibiting hTERT phosphorylation and this effect was reversed by pretreatment with NAC
Roy et al., Journal of molecular signaling 2010 : SFN inhibited phosphorylation of AKT and ERK, and activated FOXO transcription factors, leading to cell cycle arrest and apoptosis