Gene interactions and pathways from curated databases and text-mining

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ANGPT1 — CASP3

Text-mined interactions from Literome

Harfouche et al., FASEB J 2003 (MAP Kinase Signaling System) : The presence of Ang-1 ( 300 ng/ml ) significantly attenuated endothelial cell apoptosis and inhibited caspase-9 , -7, and -3 activation
Dallabrida et al., Circ Res 2005 (MAP Kinase Signaling System) : Angiopoietin-1 promoted survival of serum starved C2C12, HSM, and NCM ( MTT, trypan blue ) and prevented taxol induced apoptosis ( caspase-3 )
Parborell et al., Mol Cell Endocrinol 2011 : Moreover, ANGPT1 inhibition increased the levels of active caspase 3 and androsterone, but decreased estradiol, AKT phosphorylation and the area of smooth muscle cell actin
Lee et al., Mol Med 2011 (Myocardial Reperfusion Injury) : Angiopoietin-1 increased cardiomyocyte survival through integrin-ß1 mediated extracellular signal regulated kinase ( ERK ) phosphorylation, which inhibited caspase-9 through phosphorylation at Thr1²5 and subsequently reduced active caspase-3
Ren et al., Journal of biomedical research 2012 : Specifically, angiopoietin-1 prevented DOX induced increases in FasL and Bax levels and cleaved caspase-3 and caspase-8 levels in H9C2 cells ... Specifically, angiopoietin-1 prevented DOX induced increases in FasL and Bax levels and cleaved caspase-3 and caspase-8 levels in H9C2 cells