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Yu et al., Med Hypotheses 2009
(Bacteroidaceae Infections...) :
By utilizing the interaction between CTLA4 and B7, specific antigens can be targeted to APCs by fusion to CTLA4 and DNA vaccines encoding CTLA4 and specific antigens greatly increased the systemic antibody responses following immunization in mice
Bonelli et al., Arthritis Rheum 2013
(Arthritis, Rheumatoid) :
In addition, a direct effect of CTLA-4Ig on antigen presenting cells (APCs) could contribute to the therapeutic effect
Linsley et al., Immunity 1996
:
Cycling and directional control of CTLA-4 expression may regulate its functional interaction with APCs bearing peptide-MHC complexes of appropriate specificity and avidity