Gene interactions and pathways from curated databases and text-mining

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APCS — IDO1

Text-mined interactions from Literome

Jasperson et al., Blood 2009 (Graft vs Host Disease) : To determine whether IDO could be induced before transplantation for enhanced GVHD suppression, we first determined whether antigen presenting cells (APCs) or epithelial cells were primarily responsible for IDO expression and subsequent GVHD suppression
O'Sullivan et al., J Immunol 2011 (Autoimmune Diseases...) : After transfer, RelB and CD80/CD86-sufficient DCs restored tolerance and achieved a long-term cure of autoimmune disease through costimulation of T(EM) and Foxp3 ( + ) Treg IFN-? production, as well as induction of IDO by host APCs