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ACTA1 — ARPC4
Text-mined interactions from Literome
Boujemaa-Paterski et al., Biochemistry 2001
:
While Shigella harnesses the eukaryotic protein N-WASp to stimulate actin polymerization and filament branching through Arp2/3 complex, the Listeria surface protein
ActA directly
activates Arp2/3 complex by an unknown mechanism ... Debranching is 3-4-fold faster when
Arp2/3 is
activated by
ActA than by the C-terminal domain of N-WASp
Chong et al., Cell Host Microbe 2009
(Listeriosis) :
Furthermore, CK2 mediated phosphorylation of
ActA regulated its affinity for the actin nucleating
ARP2/3 complex , as is the case for CK2 mediated phosphorylation of WASP and WAVE