Gene interactions and pathways from curated databases and text-mining

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ATF2 — TNF

Text-mined interactions from Literome

Ivanov et al., J Biol Chem 1999 (Melanoma) : At the same time, either truncated or full-length forms of ATF2 reduced UVC induced activation of the tumor necrosis factor-alpha (TNFalpha) promoter and decreased expression of TNFalpha
Brinkman et al., J Biol Chem 1999 : The study presented here shows that autoregulation of TNF-alpha gene transcription by selective signaling through tumor necrosis factor receptor 1 (TNFR1) requires p38 mitogen activated protein ( MAP ) kinase activity and the binding of the transcription factors ATF-2 and Jun to the TNF-alpha cAMP-response element ( CRE ) promoter element
Clerk et al., J Mol Cell Cardiol 1999 (MAP Kinase Signaling System) : IL-1 beta and TNF alpha stimulated the phosphorylation of c-Jun and ATF2
Fuchs et al., J Biol Chem 2000 (MAP Kinase Signaling System) : Treatment of cells with okadaic acid elevated the tumor necrosis factor alpha induced ATF2 level and the extent of its specific N-terminal phosphorylation
Ivanov et al., Oncogene 2000 (Melanoma) : We recently demonstrated that through up-regulation of TNFalpha , ATF2 increases the resistance of late stage melanoma cells to apoptosis induced by UV-irradiation
Valladares et al., Endocrinology 2000 : In addition, TNFalpha induced activating transcription factor-1 phosphorylation is extensively decreased by SB203580
Miakotina et al., Am J Physiol Lung Cell Mol Physiol 2002 : Finally, TNF-alpha increased the phosphorylation of ATF-2 , a transcription factor that is a p38 MAPK substrate
Kumawat et al., J Biol Chem 2010 (Acquired Immunodeficiency Syndrome...) : Nef inhibits ASK1/p38 MAPK dependent Mtb induced TNF-alpha production probably by inhibiting binding of ATF2 to the TNF-alpha promoter
Lee et al., J Nutr Biochem 2013 (Pneumonia) : In addition, EGCG also attenuated TNF-a induced oxidative stress, p47(phox) translocation, MAPKs activation, and STAT-3 and activating transcription factor (ATF)2 phosphorylation
Tsai et al., Mol Cell Biol 1996 : Tumor necrosis factor alpha gene regulation in activated T cells involves ATF-2/Jun and NFATp ... This study is the first demonstration of a role for ATF-2 in TNF-alpha gene transcription and of a functional interaction between ATF-2/Jun and NFATp
Tsai et al., Mol Cell Biol 1996 (Lymphoma) : Cell-type-specific regulation of the human tumor necrosis factor alpha gene in B cells and T cells by NFATp and ATF-2/JUN
Min et al., J Immunol 1997 : In human endothelial cells, TNF rapidly induces N-terminal domain phosphorylation of both c-Jun and ATF2